Liver cancer is one of the most malignant types of cancer, accounting for over 700,000 annual deaths worldwide (Ferlay et al., 2015). The most common form of liver cancer is Hepatocellular Carcinoma (HCC), which has emerged as the third leading cause of cancer-associated mortality worldwide. The lack of effective clinical treatments requires a further understanding of novel targets against hepatocellular carcinoma progression. This research investigates the relationship between TGF-β1 and the expression of the COL1A1 gene in HCC progression. To view my grant proposal in a larger browser click here!