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Scientific research on treatments for depression has grown dramatically over the past decade. However, many naturally occurring potential medications remain under-researched. Two such categories are prebiotics and probiotics. To fully harness their potential, it is essential to understand their synergy and their effects on depression in relation to gut health. As a result, deeper exploration is needed in three key areas: the effects of combining these treatments, comparisons between individual treatments and antidepressants, and the connection between specific treatments and gut health, which could pave the way for precision medicine in this area of neuroscience. Additionally, these two treatments are generally safe and widely accessible, making them a viable option in developing countries where antidepressants may be scarce.
