How Modifications in Ethnic Diet Alter Drug Efficiency in Individuals

Importance

This project is important because it bridges pharmacogenetics with nutrigenomics (diet-gene interactions), which has not been thoroughly researched in connection with disease and specialized medicine. As of now, a majority of pharmacogenetic studies, such as Swen et al. (2023), are limited to the effect of genetic testing on drug response, which is reliant on European data, disregarding other unique populations (Gray, 2024). The effect of ethnic dietary compounds on gene expression, metabolism rate, and physical response to medicine could allow medical professionals to create culturally informed patient outcomes and treatments. Furthermore, these observations can be integrated with preexisting cytochrome P450 minor allele frequency data to make inferences on ideal treatment dosages with increased accuracy.

Project Notes

Grant Proposal