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research

Research

Our goal is tounderstand the molecular mechanisms that regulate the arms race between a pathogen and the host immune cells.
We use genetic and genomic approaches to identify genes and map networks that systematically decipher how a benign commensal becomes a serious pathogen in the context of a host organism.

publication

Publications

Adhesion to the surfaces of medical devices and host cells is crucial for fungal biofilms. We have identified filastatin, a novel therapeutic and/or as a coating for medical devices that inhibits adhesion to polystyrene, silicone mesh, and cultured human epithelial cells (PNAS 110(33): 13594-13599).

group

Group

Students take center stage.
We include students at every level of their scientific careers who are motivated to make important discoveries.

group

Contact

WPI
100 Institute Rd.
Worcester MA
01609 USA
rpr@wpi.edu

 

Broad Institute
7 Cambridge Center‬

Cambridge MA
02143 USA
rpr@broadinstitute.org