Curriculum Vitae

Courses

BE 2604 Foundations in Biological Transport Phenomena

BE 4828 Biomaterials-Tissue Interactions

BE 1001 Intro to Biomedical Engineering

BE 591 Graduate Seminar

BE 550 Tissue Engineering

MQPs, IQPs, Sufficiencies

1. MQP Co-Advisor, “Performance of Tissue Approximation Techniques”, Jaqueline M. Flatow, Julie K. Salisbury, Burt S. Raymond, A00, B00, C01 and D01, #SQK-9714, Advisor: Sean S. Kohles. Honorable Mention – Project Presentation Day 2001
   
   
2. MQP Advisor, “Biomechanics of Bilayered Delamination of the Dermal-Epidermal Interface in Normal and Engineered Skin”, Brett Downing, Kevin Cornwell, A01, B01, C02, and D02, #GXP-0101 Honorable Mention – Project Presentation Day 2002
   
   
3. MQP Advisor, “Characterization of Biomaterials for Tissue Approximation”, Theresa C. Green, Tiffany W. Howland, Jayne N. McAlary, A01, B01, C02, and D02, #GXP-0102
   
   
4. MQP Advisor, “Design of a Human Lumbar Disc Prosthesis”, Jessica Brown, Brian Pitreau, Elaine Warner, A01, B01, C02, and D02, Co-Advisor: Christopher H. Sotak (WPI), #GXP-0103
   
   
5. MQP Advisor, “Design of a Human Lumbar Disc Prosthesis”, Jennifer A. Gray, Keith L. Hines, Katherine L. Mirtle, Rachel A. Ryznal, A02, B02, C03 and D03, Co-Advisor: Christopher H. Sotak, #GXP-0104.
   
   
6. MQP Advisor, “Rational Design of Basal Lamina Analogs for Applications in Tissue Engineering”, Kristin A. Coughlan and Sarah E. Tressel, A02, B02, C03 and D03, Co-Advisor: K. L. Billiar, #GXP-0105.
   
   
7. MQP Co-Advisor, “Biomechanical Analysis to Optimize the Performance of a Sternum Fixation Device”, Erin Dupak, Najmuddin Gunja, Nicole McMahon, Shruti Pai, A03, B03, C04 and D04, #BME-0619, Advisor: Kristin Billiar. 2004 Provost’s MQP Award for Biomedical Engineering
   
   
8. MQP Advisor, “Designing a Bioreactor to Enhance Cell-Mediated Mineralization of Scaffolds for Bone Tissue Engineering”, Ian Bonzani, Kerry Malone and Sarah Walsh, A03, B03, C04 and D04, #GXP-0107.
   
   
9. MQP Co-Advisor, “Optical Ear Simulator for a Non-invasive Glucose Monitor”, Robert Degon, D04, Advisor: Robert A. Peura.
   
   
10. MQP Co-Advisor, “Earlobe Model for use with Noninvasive Glucose Monitor”, Meredith E. Hall, E04, Advisor: Robert A. Peura, # RAP-52-64
    
    
11. MQP Co-Advisor, “Design of an In Vitro System for the Evaluation of Biodegradation in Collagen Sponges Using MRI”, Laura Corsetto, Laura Desi, Stuart Howes, Mark Russo, A04, B04, C05 and D05, #CYS-535, Advisor: Christopher Sotak.
    
    
12. MQP Advisor, “Designing an Extrusion System to Optimize the Production of Self-Assembled Collagen Microthreads”, William Bishop, Diana Camire, Ngoc Chau Duong, Jason Robinson, A04, B04, C05, and D05, #GXP-0508
    
    
13. IQP Advisor, “Partnerships Implementing Engineering Education”, Daniel Bartl, Andrea Flynn, Richard McCleary, Johnny Paretti, Paul Ragaglia, A04, B04, C05 and D05, #GXP-PIE4.
    
    
14. IQP Advisor, "Partnerships Implementing Engineering Education", Kelly Head, Shannon O'Connell, Denise Marsh, Cheri Geiger, A, B, C and D terms, 2005-06, #GXP-PIE1.
15. MQP Advisor, "Design of a bandage that inhibits microbial infection", Marcella Corcoran, Whitney Moore, Sarah Stout, A, B, C and D terms, 2005-06, #GXP-0610
16. MQP Co-Advisor, "A Method for Determining the Effect of Stiffness and Stretch on Cell Phenotype", Molly Conforte, Maria Mavromatis, Jacquelyn Youssef, A, B, C and D terms, 2005-06, #KLB-0501, Advisor: Kristin Billiar.

Teaching Recognition and Awards

Honorable Mention, 2001 Provost’s MQP Award

MQP Co-Advisor, “Performance of Tissue Approximation Techniques”, Jackie Flatow, Julie Salisbury and Burt Raymond, 2001,

Honorable Mention, 2002 Provost’s MQP Award

MQP Advisor, “Biomechanics of Bilayered Delamination of the Dermal-Epidermal Interface in Normal and Engineered Skin”, Kevin Cornwell and Brett Downing, A, B, C and D terms, 2001-2002, #GXP0101.

2004 Provost’s MQP Award for Biomedical Engineering

MQP Co-Advisor, “Biomechanical Analysis to Optimize the Performance of a Sternum Fixation Device”, Erin Dupak, Najmuddin Gunja, Nicole McMahon, Shruti Pai, A03, B03, C04 and D04, #BME-0619, Advisor: Kristin Billiar.

MS Thesis Presentation Award, 2004 BME Project Presentation Day

Graduate Research Major Advisor, "The Influence of Membrane Microtopography on Keratinocyte Proliferation and Differentiation", Student: Brett Downing

Ph.D. Thesis Presentation Award, 2004 BME Project Presentation Day

Graduate Research Major Advisor, " Characterizing Fibroblast Migration on Discrete Collagen Threads for Applications in Tissue Regeneration", Student: Kevin Cornwell

2004 Trustees’ Award for Outstanding Academic Advising

Peer-Reviewed Articles Published or in press

Pins, GD, Bush, KA, Cunningham, L.P., and Campagnola, P.J.,

"Multiphoton Excited Fabricated Nano and Micro Patterned Extracellular Matrix Proteins Direct Cellular Morphology". Journal of Biomedical Materials Research, Accepted (2005).

Cornwell, KG and Pins, GD,

"Crosslinking of discrete self-assembled collagen threads: Effects on mechanical strength and cell-matrix interactions" Journal of Biomedical Materials Research, under revision (2005).

Pai, S., Gunja, N., Dupak, E., McMahon, N., Lalikos, J., Dunn, R., Francalancia, N., Pins GD and Billiar, K.,

"A Mechanical Study of Rigid Plate Configurations for Sternal Fixation", Journal of Biomechanics, submitted (2005).

Pai, S., Gunja, N., Dupak, E., McMahon, N., Lalikos, J., Dunn, R., Francalancia, N., Pins GD and Billiar, K.,

“The Effect of Rigidity in Fixation Devices on Sternal Separation”, Annals of Thoracic Surgery, submitted (2005).

Basu, S, Cunningham, L.P., Pins, G.D., Bush, K.A., Howell, A.R., Campagnola, P.J.,

“Multi-photon Excited Fabrication of Collagen Matrices Crosslinked by a Modified Benzophenone Dimer: Bioactivity and Enzymatic Degradation.” Biomacromolecules, accepted (2005).

Downing, BR, Cornwell, KG, Toner, M. and Pins, GD,

The influence of microtextured basal lamina analog topography on keratinocyte function and epidermal regeneration. Journal of Biomedical Materials Research, 72A: 47-56 (2005).

Cornwell, KG, Downing, BR, and Pins, GD,

“Characterizing fibroblast migration on discrete collagen threads for applications in tissue regeneration.” Journal of Biomedical Materials Research, 71A: 55-62 (2004).

Pins GD, Collins-Pavao ME, Van De Water L, Yarmush, ML, and Morgan JR,

“Plasmin triggers rapid contraction and degradation of fibroblast populated collagen lattices.” Journal of Investigative Dermatology, 114: 647-53 (2000).

Pins GD, Toner, M, and Morgan, JR,

“Microfabrication of an analog of the basal lamina: Biocompatible membranes with complex topographies.” FASEB Journal, 14: 593-602 (2000).

Pins GD, Christiansen DL, Patel R, and Silver FH,

“Self-assembly of collagen fibers: Influence of fibrillar alignment and decorin on mechanical properties.” Biophysical Journal, 73: 2164-2172 (1997).

Pins GD, Huang EK, Christiansen DL, and Silver FH,

“The effects of static axial strain on the tensile properties and failure mechanisms of self-assembled collagen fibers.” Journal of Applied Polymer Science, 63: 1429-1440 (1997).

Pins GD and Silver FH,

“A self-assembled collagen scaffold suitable for use in soft and hard tissue replacement.” Materials Science and Engineering, C3: 101–107 (1995).

Wang M-C, Pins GD, and Silver FH,

“Preparation of fibrin glue: The effects of calcium chloride and sodium chloride.” Materials Science and Engineering, C3: 131-135 (1995).

Silver FH, Wang M-C, and Pins GD,

“Preparation of fibrin glue: A study of chemical and physical methods.” Journal of Applied Biomaterials, 6: 175–183 (1995).

Silver FH, Pins GD, Olson RM, and D'Aguillo A,

“Silicone gel-filled implants: Is local inflammation associated with fat necrosis?” The Breast Journal, 1: 17-21 (1995).

Rizvi AH, Pins GD, and Silver FH,

“Peripheral nerve regeneration in the presence of collagen fibers: Effect of removal of the distal nerve stump.” Clinical Materials, 16: 73-80 (1994).

Wang M-C, Pins GD, and Silver FH,

“Collagen fibers with improved strength for the repair of soft tissue injuries.” Biomaterials, 15: 507-512 (1994).

Silver FH, LiBrizzi JJ, Pins GD, Wang M-C and Benedetto D,

“Physical properties of hyaluronic acid and hydroxypropylmethylcellulose in solution: Evaluation of coating and lubricating ability.” Journal of Applied Biomaterials, 5: 89-98 (1994).

Christiansen DL, Pins GD, and Silver FH,

“A simple freeze fracture technique for scanning electron microscopy of collagenous biomaterials.” Cells and Materials, 3: 189-191 (1993).

Christiansen DL, Pins GD, Wang M-C, Dunn MG, Silver FH,

“Collagenous biocomposites for the repair of soft tissue injury.” Materials Research Society Symposium Proceedings, 252: 151-158 (1992).

Review Articles, Book Chapters and Invited Papers published or in press

• Pins, GD, “An Analog of the Basal Lamina”, Science and Medicine, 7: 6-7 (2000).
• Silver FH, Wang M-C, and Pins GD, “Preparation and use of fibrin glue in surgery: A review.” Biomaterials, 16: 891-903 (1995).
• Silver FH, Pins GD, Wang M-C, and Christiansen DL, “Collagenous biomaterials as models of tissue inducing implants.” in Encyclopedic Handbook of Biomaterials and Bioengineering, Part A: Materials, Wise DL, et al., Eds., Marcel Dekker, Inc., New York, 36: 1245-1266 (1995).
• Silver FH and Pins GD, “Cell growth on collagen: A review of tissue engineering using scaffolds containing extracellular matrix.” Journal of Long-Term Effects of Medical Implants, 2: 67-80 (1992).

Patents

• Microfabricated Membranes and Matrices, Morgan, JR and Pins, GD, US Patent # 6,479,072, Nov. 12, 2002,

Peer Reviewed Abstracts and Conference Proceedings

1. Campagnola, PJ., Cunningham, L., Pins, GD., and Bush, KA.,, "Multiphoton Fabricated Functional Tissue Engineering Scaffolds Synthesized from Crosslinked Extracellular Matrix Proteins", Submitted 231st ACS National Meeting, Atlanta, GA
   
   
2. Pins, GD "Designing Collagen Scaffolds to Enhance Tissue Regeneration.", Accepted 2005 Fall Meeting, Materials Research Society, Boston, MA
   
   
3. Campagnola, PJ., Cunningham, L., Pins, GD., and Bush, KA.,, "Multiphoton Excited Fabricated Nano and Micro Patterned Extracellular Matrix Proteins Direct Cellular Morphology", Accepted 2005 Fall Meeting, Materials Research Society, Boston, MA.
   
   
4. Downing, BR, Soto, E., Bush, KA., McGimpsey, G., and Pins, GD "Self-assembled monolayers presenting precisely defined functional groups modulate protein binding and direct cell attachment and spreading" surface wettabilities direct keratinocyte attachment and spreading.", Accepted 2005 Fall Meeting, Materials Research Society, Boston, MA.
   
   
5. Coburn, J., Bush, KA., and Pins, GD., (2005) "Establishing a Quantitative Link between Fibronectin Concentration and Active Binding Sites for Keratinocyte Adhesion to Collagen-Glycosaminoglycan Membranes", 2005 Biomedical Engineering Society Meeting, Baltimore, MD.
   
   
6. Kinneberg, K., Cornwell, KG., and Pins, GD., (2005) "Development of a Discrete Thread Cell Attachment Assay", 2005 Biomedical Engineering Society Meeting, Baltimore, MD.
   
   
7. Cornwell, KG, and Pins, GD, (2005) "Crosslinking discrete collagen threads: Effects on mechanical strength and cell matrix interactions 2005 Biomedical Engineering Society Meeting, Baltimore, MD.
   
   
8. Bush, KA., Walsh, SE., Downing, BR., and Pins, GD., (2005) "Characterizing Keratinocyte Adhesion in Response to Basal Lamina Composition", 2005 Biomedical Engineering Society Meeting, Baltimore, MD.
   
   
9. Downing, B.R., Howes, S., Toner, M. and Pins, G.D.. (2005) "The Influence of Collagen Membrane Microtopography on Keratinocyte Function." 2005 Biomedical Engineering Society Meeting, Baltimore, MD.
   
   
10. Campagnola, PJ., Basu, S., Cunningham, L., Pins, GD., (2004), “Tissue Engineering Applications of Multiphoton Nanofabrication”, 2004 Fall Meeting, Materials Research Society, Boston, MA.
    
    
11. Cornwell, K. G., Downing, B. R. and Pins, G.D. (2004) “Characterizing Fibroblast Migration on Collagen Threads for Applications in Tissue Engineering” 2004 Biomedical Engineering Society Meeting, Philadelphia, PA.
    
    
12. Bush, K.A. Balestrini, J.L., Walsh, S.E., Downing, B.R., and Pins G.D. (2004) Characterization of Keratinocyte Adhesion on Surface Modified Basal Lamina Analogs”, 2004 Biomedical Engineering Society Meeting, Philadelphia, PA.
    
    
13. Downing, B.R., Cornwell, K. G., Toner, M. and Pins, G.D.. (2004) “The Influence of Collagen Membrane Microtopography on Keratinocyte Function.” 2004 Biomedical Engineering Society Meeting, Philadelphia, PA.
    
    
14. Pai, S., Gunja, N., McMahon, N., Dupak, E., Pins GD and Billiar, K., Francalancia, N., Lalikos, J., Dunn, R.,. (2004) “A Biomechanical Study of Rigid and Non-Rigid Sternal Fixation Techniques”, 45th Annual New England Society of Plastic and Reconstructive Surgeons, Berkshires, MA, June 2004
    
    
15. Bonzani, I, Malone, K, Walsh, S, Pavao, MC, and Pins GD (2004) “Designing a Bioreactor to Enhance Cell-Mediated Mineralization of Scaffolds for Bone Tissue Engineering 30th Annual Northeast Bioengineering Conference, Springfield, MA, April 2004.
    
    
16. Huelsman, M, Gonzalez, K, Bonzani, I., Malone, K., Walsh, S., Pins, GD, and Pavao, MC, (2004) “Odontoblast-like Cell Differentiation in a Collagen Scaffold”, 30th Annual Northeast Bioengineering Conference, Springfield, MA, April 2004.
    
    
17. Gunja, N., Pai, S., McMahon, N., Dupak, E., Lalikos, J., Francalancia, N., Dunn, R., Pins GD and Billiar, K. (2004) “A Biomechanical Study of a Rigid Plating System for Sternal Fixation”, 30th Annual Northeast Bioengineering Conference, Springfield, MA, April 2004.
    
    1st Place Award, Undergraduate Oral Presentation Competition, 30th Annual Northeast Bioengineering, Conference, Springfield, MA, 2004.
    
    
18. Downing, B.R., Toner, M. and Pins, G.D.. The Influence of Collagen Membrane Microtopography on Keratinocyte Proliferation and Differentiation. Materials Research Society Symposium Proceedings, EXS-1, F7.5.1 – F. 7.5.3 (2004).
    
    
19. Balestrini, J.L., Walsh, S.E., Downing, B.R., Tressel, S.L., Coughlan, K.A., Billiar, K.L., and Pins G.D. Characterizing Surface Modifications of Basal Lamina Analogs to Enhance Keratinocyte Function and Tissue Regeneration. Materials Research Society Symposium Proceedings, EXS-1, F8.8.1 – F. 8.8.3 (2004).
    
    
20. Cornwell, K. and Pins, G.D.. Characterizing Fibroblast Attachment, Proliferation, and Migration on Self-Assembled Collagen Threads. Materials Research Society Symposium Proceedings, EXS-1, F3.11.1 – F. 3.11.3 (2004).
    
    
21. Throm, A.M., Downing, B.R. and Pins, G.D.. A Method for Fabricating Microtextured Basal Lamina Analogs with Submicron Porous Architecture. Materials Research Society Symposium Proceedings, EXS-1, F7.4.1 – F. 7.4.3 (2004).
    
    
22. Tressel, SL, Coughlan, KA, Billiar, KL, and Pins GD (2003) “A High-Throughput Method of Characterizing Biomimetic Surface Modifications to Basal Lamina Analogs for Applications in Tissue Engineering”, 29th Annual Northeast Bioengineering Conference, Newark, NJ, March 2003.
    
    
23. Throm, AM, and Pins GD (2003) “A Method for Fabricating Collagen Membranes with Microporous Structure: Applications in Tissue Engineering”, 29th Annual Northeast Bioengineering Conference, Newark, NJ, March 2003.
    
    
24. Cornwell, KG, Savage, M, Billiar, KL, and Pins GD, (2003) “A Device for Studying Cyclic Mechanical Loading of Cells Seeded on Collagen Fibers”, 29th Annual Northeast Bioengineering Conference, Newark, NJ, March 2003.
    
    
25. Pins GD, Toner M, Morgan, JR, (2002) “Microfabrication of Basal Lamina Analogs: Applications for Tissue Engineering”2002 Spring Meeting, Materials Research Society, San Francisco, CA.
    
    
26. Morgan JM*, Eming S, Medalie D, Andreadis S, Hamoen K, Pins G, (1998) “Growth Factor Delivery from Genetically Modified Skin Grafts.” 1998 Biomedical Engineering Society Meeting, Cleveland, OH.
    
    
27. Bordon DM*, Silver FH, Pins GD, Huang EK and Christiansen DL. (1996) “Viscoeleastic Behavior of in vitro self-assembled type I collagen fibers.” 1996 Fall Meeting, Materials Research Society, Boston, MA.
    
    
28. Pins GD, Wey PD*, Aneskievich BJ, and Borah GL. (1996) “Fibroblast attachment, proliferation and migration on type I collagen fibers.” 41st Annual Meeting, Plastic Surgery Research Council, St. Louis, MO.
    
    
29. Huang EK*, Pins GD, Silver FH, and Christiansen DL. (1996), “Effects of incubation time on in vitro self-assembly of type I collagen molecules.” Fifth World Biomaterials Congress, Toronto, ONT.
    
    
30. Pins GD*, Christiansen DL, Patel R, and Silver FH. (1995) “Production of a novel, self-assembled, collagenous matrix mimicking the hierarchical structure of native aligned connective tissue.” 1995 Fall Meeting, Materials Research Society, Boston, MA.
    
    
31. Christiansen DL*, Pins GD, Huang EK, and Silver FH. (1995) “A novel self-assembled collagenous matrix which serves as a template for oriented growth of hydroxyapatite crystal.” 1995 Fall Meeting, Materials Research Society, Boston, MA.
    
    
32. Pins GD* and Silver FH (1994) “An evaluation of a self-assembled collagen scaffold.” 1994 Fall Meeting, Materials Research Society, Boston, MA.
    
    
33. Christiansen DL, Pins GD*, Wang M-C, Dunn MG, and Silver FH. (1992) “Collagenous biocomposites for the repair of soft tissue injury.” 1991 Fall Meeting, Materials Research Society, Boston, MA.